Human in vitro assays

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title=””>href=”#footnote_4510_123″ id=”identifier_4510_123″ class=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_4508_123″ id=”identifier_4508_123″ class=”footnote-link footnote-identifier-link” title=””>a href=”#footnote_4506_123″ id=”identifier_4506_123″ class=”footnote-link footnote-identifier-link” title=””>“>t;”>ass=”footnote-link footnote-identifier-link” title=””><a>a href=”#footnote_4492_123″ id=”identifier_4492_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_4484_123″ class=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””><a>a href=”#footnote_4478_123″ id=”identifier_4478_123″ class=”footnote-link footnote-identifier-link” title=””>_123″ id=”identifier_4470_123″ class=”footnote-link footnote-identifier-link” title=””>_123″ id=”identifier_4469_123″ class=”footnote-link footnote-identifier-link” title=”-“>link footnote-identifier-link” title=””>” id=”identifier_4466_123″ 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title=””>href=”#footnote_4422_123″ id=”identifier_4422_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_4414_123″ id=”identifier_4414_123″ class=”footnote-link footnote-identifier-link” title=””>ote_4412_123″ id=”identifier_4412_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_4410_123″ class=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>href=”#footnote_4404_123″ id=”identifier_4404_123″ class=”footnote-link footnote-identifier-link” title=””>ote_4400_123″ id=”identifier_4400_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_4398_123″ id=”identifier_4398_123″ class=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_4394_123″ id=”identifier_4394_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_4392_123″ id=”identifier_4392_123″ class=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link 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title=””>< href=”#footnote_4364_123″ id=”identifier_4364_123″ class=”footnote-link footnote-identifier-link” title=””>note_4362_123″ id=”identifier_4362_123″ class=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_4360_123″ id=”identifier_4360_123″ class=”footnote-link footnote-identifier-link” title=””>otnote_4358_123″ id=”identifier_4358_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_4352_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_4350_123″ id=”identifier_4350_123″ class=”footnote-link footnote-identifier-link” title=””>note_4348_123″ id=”identifier_4348_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>otnote_4344_123″ id=”identifier_4344_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_4340_123″ id=”identifier_4340_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_4338_123″ id=”identifier_4338_123″ class=”footnote-link footnote-identifier-link” title=””>ref=”#footnote_4336_123″ id=”identifier_4336_123″ class=”footnote-link footnote-identifier-link” title=””>note_4334_123″ id=”identifier_4334_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_4332_123″ id=”identifier_4332_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>d=”identifier_4328_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_4326_123″ id=”identifier_4326_123″ class=”footnote-link footnote-identifier-link” title=””>4_123″ id=”identifier_4324_123″ class=”footnote-link footnote-identifier-link” title=””>ref=”#footnote_4322_123″ id=”identifier_4322_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_4320_123″ id=”identifier_4320_123″ class=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_4318_123″ id=”identifier_4318_123″ class=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_4316_123″ id=”identifier_4316_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_4312_123″ id=”identifier_4312_123″ class=”footnote-link footnote-identifier-link” title=””>ote_4306_123″ id=”identifier_4306_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_4304_123″ class=”footnote-link footnote-identifier-link” title=””>note_4302_123″ id=”identifier_4302_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>f=”#footnote_4298_123″ id=”identifier_4298_123″ class=”footnote-link footnote-identifier-link” title=””>note_4296_123″ id=”identifier_4296_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_4294_123″ id=”identifier_4294_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>otnote_4288_123″ id=”identifier_4288_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_4286_123″ id=”identifier_4286_123″ class=”footnote-link footnote-identifier-link” title=””>ote_4284_123″ id=”identifier_4284_123″ class=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_4282_123″ id=”identifier_4282_123″ class=”footnote-link footnote-identifier-link” title=””>note_4280_123″ id=”identifier_4280_123″ class=”footnote-link footnote-identifier-link” title=””>lass=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_4274_123″ id=”identifier_4274_123″ class=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_4272_123″ id=”identifier_4272_123″ class=”footnote-link footnote-identifier-link” title=””>note_4270_123″ id=”identifier_4270_123″ class=”footnote-link footnote-identifier-link” title=””>ote_4268_123″ id=”identifier_4268_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_4266_123″ class=”footnote-link footnote-identifier-link” 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title=””>lass=”footnote-link footnote-identifier-link” title=””>ote_3976_123″ id=”identifier_3976_123″ class=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_3974_123″ id=”identifier_3974_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_3970_123″ id=”identifier_3970_123″ class=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>f=”#footnote_3966_123″ id=”identifier_3966_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_3962_123″ id=”identifier_3962_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_3954_123″ id=”identifier_3954_123″ class=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>otnote_3950_123″ id=”identifier_3950_123″ class=”footnote-link footnote-identifier-link” title=””>ote_3948_123″ id=”identifier_3948_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_3944_123″ id=”identifier_3944_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_3936_123″ id=”identifier_3936_123″ class=”footnote-link footnote-identifier-link” title=””>note_3934_123″ id=”identifier_3934_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>ote_3926_123″ id=”identifier_3926_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_3922_123″ id=”identifier_3922_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_3916_123″ id=”identifier_3916_123″ class=”footnote-link footnote-identifier-link” title=””>ote_3914_123″ id=”identifier_3914_123″ class=”footnote-link footnote-identifier-link” title=””>ote_3912_123″ id=”identifier_3912_123″ class=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_3910_123″ id=”identifier_3910_123″ class=”footnote-link 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id=”identifier_3804_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_3800_123″ id=”identifier_3800_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_3798_123″ id=”identifier_3798_123″ class=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>f=”#footnote_3794_123″ id=”identifier_3794_123″ class=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_3792_123″ id=”identifier_3792_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_3790_123″ id=”identifier_3790_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_3788_123″ id=”identifier_3788_123″ class=”footnote-link footnote-identifier-link” title=””>ote_3786_123″ id=”identifier_3786_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_3784_123″ class=”footnote-link footnote-identifier-link” title=””>< 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href=”#footnote_3752_123″ id=”identifier_3752_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_3750_123″ id=”identifier_3750_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_3746_123″ id=”identifier_3746_123″ class=”footnote-link footnote-identifier-link” title=””>ote_3744_123″ id=”identifier_3744_123″ class=”footnote-link footnote-identifier-link” title=””>otnote_3742_123″ id=”identifier_3742_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_3740_123″ class=”footnote-link footnote-identifier-link” title=””>note_3738_123″ id=”identifier_3738_123″ class=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_3736_123″ id=”identifier_3736_123″ class=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>ote_3730_123″ id=”identifier_3730_123″ class=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_3728_123″ id=”identifier_3728_123″ 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class=”footnote-link footnote-identifier-link” title=””>ote_3698_123″ id=”identifier_3698_123″ class=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_3696_123″ id=”identifier_3696_123″ class=”footnote-link footnote-identifier-link” title=””>ref=”#footnote_3690_123″ id=”identifier_3690_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_3688_123″ id=”identifier_3688_123″ class=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_3682_123″ id=”identifier_3682_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_3676_123″ id=”identifier_3676_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_3674_123″ id=”identifier_3674_123″ class=”footnote-link footnote-identifier-link” title=””>ote_3672_123″ id=”identifier_3672_123″ class=”footnote-link footnote-identifier-link” title=””>otnote_3670_123″ id=”identifier_3670_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_3668_123″ class=”footnote-link footnote-identifier-link” title=””>note_3666_123″ id=”identifier_3666_123″ class=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_3664_123″ id=”identifier_3664_123″ class=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>ote_3658_123″ id=”identifier_3658_123″ class=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_3656_123″ id=”identifier_3656_123″ class=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_3654_123″ id=”identifier_3654_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_3650_123″ id=”identifier_3650_123″ class=”footnote-link footnote-identifier-link” title=””>=”identifier_3648_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_3646_123″ id=”identifier_3646_123″ 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title=””>ass=”footnote-link footnote-identifier-link” title=””><a>a href=”#footnote_3604_123″ id=”identifier_3604_123″ class=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_3602_123″ id=”identifier_3602_123″ class=”footnote-link footnote-identifier-link” title=””>otnote_3600_123″ id=”identifier_3600_123″ class=”footnote-link footnote-identifier-link” title=””>note_3598_123″ id=”identifier_3598_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_3594_123″ id=”identifier_3594_123″ class=”footnote-link footnote-identifier-link” title=””>lass=”footnote-link footnote-identifier-link” title=””>f=”#footnote_3590_123″ id=”identifier_3590_123″ class=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_3588_123″ id=”identifier_3588_123″ class=”footnote-link footnote-identifier-link” title=””>link footnote-identifier-link” title=””>href=”#footnote_3578_123″ id=”identifier_3578_123″ class=”footnote-link footnote-identifier-link” title=””>ote_3576_123″ id=”identifier_3576_123″ class=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_3574_123″ id=”identifier_3574_123″ class=”footnote-link footnote-identifier-link” title=””>ref=”#footnote_3568_123″ id=”identifier_3568_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_3566_123″ id=”identifier_3566_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_3564_123″ id=”identifier_3564_123″ class=”footnote-link footnote-identifier-link” title=””>ref=”#footnote_3562_123″ id=”identifier_3562_123″ class=”footnote-link footnote-identifier-link” title=””>note_3560_123″ id=”identifier_3560_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_3558_123″ id=”identifier_3558_123″ class=”footnote-link footnote-identifier-link” title=””>ref=”#footnote_3556_123″ id=”identifier_3556_123″ class=”footnote-link footnote-identifier-link” title=””>note_3554_123″ id=”identifier_3554_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_3552_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_3548_123″ id=”identifier_3548_123″ class=”footnote-link footnote-identifier-link” title=””>=”identifier_3546_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_3544_123″ id=”identifier_3544_123″ class=”footnote-link footnote-identifier-link” title=””>note_3542_123″ id=”identifier_3542_123″ class=”footnote-link footnote-identifier-link” title=””>lass=”footnote-link footnote-identifier-link” title=””>f=”#footnote_3538_123″ id=”identifier_3538_123″ class=”footnote-link footnote-identifier-link” title=””>=”#footnote_3536_123″ id=”identifier_3536_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>ote_3532_123″ id=”identifier_3532_123″ class=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_3530_123″ id=”identifier_3530_123″ class=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_3528_123″ id=”identifier_3528_123″ class=”footnote-link footnote-identifier-link” title=””>note_3526_123″ id=”identifier_3526_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_3524_123″ id=”identifier_3524_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_3522_123″ id=”identifier_3522_123″ class=”footnote-link footnote-identifier-link” title=””>ote_3520_123″ id=”identifier_3520_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_3518_123″ class=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>href=”#footnote_3514_123″ id=”identifier_3514_123″ class=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>f=”#footnote_3508_123″ id=”identifier_3508_123″ class=”footnote-link 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href=”#footnote_3480_123″ id=”identifier_3480_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_3474_123″ id=”identifier_3474_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_3472_123″ id=”identifier_3472_123″ class=”footnote-link footnote-identifier-link” title=””>t;”>d=”identifier_3462_123″ class=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>a href=”#footnote_3458_123″ id=”identifier_3458_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_3454_123″ id=”identifier_3454_123″ class=”footnote-link footnote-identifier-link” title=””>“>“>“>“>“>“>“>“>“>“>“>“>ot;”>#footnote_3446_123″ id=”identifier_3446_123″ class=”footnote-link footnote-identifier-link” title=””>note_3444_123″ id=”identifier_3444_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>d=”identifier_3440_123″ class=”footnote-link footnote-identifier-link” title=””>=”identifier_3436_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_3434_123″ id=”identifier_3434_123″ class=”footnote-link footnote-identifier-link” title=””>note_3432_123″ id=”identifier_3432_123″ class=”footnote-link footnote-identifier-link” title=””>ote_3430_123″ id=”identifier_3430_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_3428_123″ id=”identifier_3428_123″ class=”footnote-link footnote-identifier-link” title=””>=”identifier_3426_123″ class=”footnote-link footnote-identifier-link” title=””>ote_3424_123″ id=”identifier_3424_123″ class=”footnote-link footnote-identifier-link” title=””>ote_3420_123″ id=”identifier_3420_123″ class=”footnote-link footnote-identifier-link” title=””>ot;”>#footnote_3416_123″ id=”identifier_3416_123″ class=”footnote-link footnote-identifier-link” title=””>“#footnote_3414_123″ id=”identifier_3414_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_3408_123″ id=”identifier_3408_123″ class=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>lass=”footnote-link footnote-identifier-link” title=””>href=”#footnote_3402_123″ id=”identifier_3402_123″ class=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>a href=”#footnote_3396_123″ id=”identifier_3396_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_3388_123″ id=”identifier_3388_123″ class=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_3382_123″ id=”identifier_3382_123″ class=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>d=”identifier_3378_123″ class=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_3376_123″ id=”identifier_3376_123″ class=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_3372_123″ id=”identifier_3372_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_3370_123″ id=”identifier_3370_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_3368_123″ id=”identifier_3368_123″ class=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_3366_123″ id=”identifier_3366_123″ class=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_3364_123″ id=”identifier_3364_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_3362_123″ id=”identifier_3362_123″ class=”footnote-link footnote-identifier-link” title=””>note_3358_123″ id=”identifier_3358_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_3356_123″ 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id=”identifier_3326_123″ class=”footnote-link footnote-identifier-link” title=””>otnote_3324_123″ id=”identifier_3324_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_3322_123″ class=”footnote-link footnote-identifier-link” title=””>note_3320_123″ id=”identifier_3320_123″ class=”footnote-link footnote-identifier-link” title=””>lass=”footnote-link footnote-identifier-link” title=””>ote_3316_123″ id=”identifier_3316_123″ class=”footnote-link footnote-identifier-link” title=””>=”#footnote_3312_123″ id=”identifier_3312_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_3310_123″ id=”identifier_3310_123″ class=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_3308_123″ id=”identifier_3308_123″ class=”footnote-link footnote-identifier-link” title=””>otnote_3306_123″ id=”identifier_3306_123″ class=”footnote-link footnote-identifier-link” title=””>=”#footnote_3304_123″ id=”identifier_3304_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_3302_123″ id=”identifier_3302_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_3296_123″ id=”identifier_3296_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_3290_123″ id=”identifier_3290_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_3288_123″ id=”identifier_3288_123″ class=”footnote-link footnote-identifier-link” title=””>otnote_3286_123″ id=”identifier_3286_123″ class=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_3284_123″ id=”identifier_3284_123″ class=”footnote-link footnote-identifier-link” title=””>note_3282_123″ id=”identifier_3282_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_3280_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_3276_123″ id=”identifier_3276_123″ class=”footnote-link footnote-identifier-link” title=””>ote_3274_123″ id=”identifier_3274_123″ class=”footnote-link footnote-identifier-link” title=””>t;”>ass=”footnote-link footnote-identifier-link” title=””><a>a href=”#footnote_3258_123″ id=”identifier_3258_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_3250_123″ class=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””><a>a href=”#footnote_3244_123″ id=”identifier_3244_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_3236_123″ id=”identifier_3236_123″ class=”footnote-link footnote-identifier-link” title=””>=”identifier_3234_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_3232_123″ id=”identifier_3232_123″ class=”footnote-link footnote-identifier-link” title=””>note_3230_123″ id=”identifier_3230_123″ class=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_3228_123″ id=”identifier_3228_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_3224_123″ id=”identifier_3224_123″ class=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>f=”#footnote_3220_123″ id=”identifier_3220_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_3218_123″ id=”identifier_3218_123″ class=”footnote-link footnote-identifier-link” title=””>otnote_3216_123″ id=”identifier_3216_123″ class=”footnote-link footnote-identifier-link” title=””>ote_3214_123″ id=”identifier_3214_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_3212_123″ id=”identifier_3212_123″ class=”footnote-link footnote-identifier-link” title=””>otnote_3204_123″ id=”identifier_3204_123″ class=”footnote-link footnote-identifier-link” title=””>note_3202_123″ id=”identifier_3202_123″ class=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_3200_123″ id=”identifier_3200_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_3198_123″ id=”identifier_3198_123″ class=”footnote-link footnote-identifier-link” title=””>=”#footnote_3196_123″ id=”identifier_3196_123″ class=”footnote-link footnote-identifier-link” title=””>otnote_3194_123″ id=”identifier_3194_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_3192_123″ id=”identifier_3192_123″ class=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_3188_123″ id=”identifier_3188_123″ class=”footnote-link footnote-identifier-link” title=””>otnote_3186_123″ id=”identifier_3186_123″ class=”footnote-link footnote-identifier-link” title=””>note_3184_123″ id=”identifier_3184_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>d=”identifier_3180_123″ class=”footnote-link footnote-identifier-link” title=””>ref=”#footnote_3178_123″ id=”identifier_3178_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_3176_123″ id=”identifier_3176_123″ class=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>d=”identifier_3170_123″ class=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_3166_123″ id=”identifier_3166_123″ class=”footnote-link footnote-identifier-link” title=””>=”#footnote_3164_123″ id=”identifier_3164_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_3162_123″ id=”identifier_3162_123″ class=”footnote-link footnote-identifier-link” title=””>otnote_3160_123″ id=”identifier_3160_123″ class=”footnote-link footnote-identifier-link” title=””>ote_3158_123″ id=”identifier_3158_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_3156_123″ id=”identifier_3156_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_3148_123″ id=”identifier_3148_123″ class=”footnote-link footnote-identifier-link” title=””>=”identifier_3144_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_3142_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_3138_123″ class=”footnote-link footnote-identifier-link” title=””>=”identifier_3136_123″ class=”footnote-link footnote-identifier-link” title=””>ote_3134_123″ id=”identifier_3134_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_3132_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_3130_123″ id=”identifier_3130_123″ class=”footnote-link footnote-identifier-link” title=””>lass=”footnote-link footnote-identifier-link” title=””>d=”identifier_3126_123″ class=”footnote-link footnote-identifier-link” title=””>otnote_3122_123″ id=”identifier_3122_123″ class=”footnote-link footnote-identifier-link” title=””>note_3120_123″ id=”identifier_3120_123″ class=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_3118_123″ id=”identifier_3118_123″ class=”footnote-link footnote-identifier-link” title=””>link footnote-identifier-link” title=””>ote_3114_123″ id=”identifier_3114_123″ class=”footnote-link footnote-identifier-link” title=””>otnote_3112_123″ id=”identifier_3112_123″ class=”footnote-link footnote-identifier-link” title=””>t;”>d=”identifier_3106_123″ class=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>a href=”#footnote_3102_123″ id=”identifier_3102_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_3098_123″ id=”identifier_3098_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_3090_123″ class=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””><a>a href=”#footnote_3084_123″ id=”identifier_3084_123″ class=”footnote-link footnote-identifier-link” title=””>note_3082_123″ id=”identifier_3082_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>f=”#footnote_3078_123″ id=”identifier_3078_123″ class=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_3076_123″ id=”identifier_3076_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_3074_123″ id=”identifier_3074_123″ class=”footnote-link footnote-identifier-link” title=””>note_3072_123″ id=”identifier_3072_123″ class=”footnote-link footnote-identifier-link” title=””>ote_3070_123″ id=”identifier_3070_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_3068_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_3066_123″ id=”identifier_3066_123″ class=”footnote-link footnote-identifier-link” title=””>=”#footnote_3064_123″ id=”identifier_3064_123″ class=”footnote-link footnote-identifier-link” title=””>otnote_3062_123″ id=”identifier_3062_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_3060_123″ id=”identifier_3060_123″ class=”footnote-link footnote-identifier-link” title=””>ote_3058_123″ id=”identifier_3058_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_3056_123″ id=”identifier_3056_123″ class=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_3052_123″ id=”identifier_3052_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_3050_123″ id=”identifier_3050_123″ class=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_3044_123″ id=”identifier_3044_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_3042_123″ id=”identifier_3042_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_3040_123″ id=”identifier_3040_123″ class=”footnote-link footnote-identifier-link” title=””>ref=”#footnote_3038_123″ id=”identifier_3038_123″ class=”footnote-link footnote-identifier-link” title=””>note_3036_123″ id=”identifier_3036_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_3034_123″ id=”identifier_3034_123″ class=”footnote-link footnote-identifier-link” title=””>otnote_3032_123″ id=”identifier_3032_123″ class=”footnote-link footnote-identifier-link” title=””>note_3030_123″ id=”identifier_3030_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_3028_123″ id=”identifier_3028_123″ class=”footnote-link footnote-identifier-link” title=””>note_3026_123″ id=”identifier_3026_123″ class=”footnote-link footnote-identifier-link” title=””>otnote_3024_123″ id=”identifier_3024_123″ class=”footnote-link footnote-identifier-link” title=””>ote_3022_123″ id=”identifier_3022_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_3020_123″ id=”identifier_3020_123″ class=”footnote-link footnote-identifier-link” title=””>note_3018_123″ id=”identifier_3018_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_3012_123″ id=”identifier_3012_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>ote_3006_123″ id=”identifier_3006_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_3004_123″ id=”identifier_3004_123″ class=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_3000_123″ id=”identifier_3000_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_2998_123″ id=”identifier_2998_123″ class=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_2992_123″ id=”identifier_2992_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_2990_123″ id=”identifier_2990_123″ class=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_2988_123″ id=”identifier_2988_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_2986_123″ id=”identifier_2986_123″ class=”footnote-link footnote-identifier-link” title=””>ref=”#footnote_2984_123″ id=”identifier_2984_123″ class=”footnote-link footnote-identifier-link” title=””>note_2982_123″ id=”identifier_2982_123″ class=”footnote-link footnote-identifier-link” title=””>otnote_2980_123″ id=”identifier_2980_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_2978_123″ id=”identifier_2978_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>=”identifier_2974_123″ class=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_2972_123″ id=”identifier_2972_123″ class=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_2970_123″ id=”identifier_2970_123″ class=”footnote-link footnote-identifier-link” title=””>otnote_2966_123″ id=”identifier_2966_123″ class=”footnote-link footnote-identifier-link” title=””>note_2964_123″ id=”identifier_2964_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_2962_123″ id=”identifier_2962_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_2954_123″ id=”identifier_2954_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_2946_123″ id=”identifier_2946_123″ class=”footnote-link footnote-identifier-link” title=””>=”identifier_2942_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_2940_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_2936_123″ class=”footnote-link footnote-identifier-link” title=””>=”identifier_2934_123″ class=”footnote-link footnote-identifier-link” title=””>ote_2932_123″ id=”identifier_2932_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_2930_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_2928_123″ id=”identifier_2928_123″ class=”footnote-link footnote-identifier-link” title=””>lass=”footnote-link footnote-identifier-link” title=””>d=”identifier_2924_123″ class=”footnote-link footnote-identifier-link” title=””>otnote_2920_123″ id=”identifier_2920_123″ class=”footnote-link footnote-identifier-link” title=””>note_2918_123″ id=”identifier_2918_123″ class=”footnote-link footnote-identifier-link” title=””>“>“>t;”>d=”identifier_2912_123″ class=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>a href=”#footnote_2908_123″ id=”identifier_2908_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_2904_123″ id=”identifier_2904_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_2896_123″ class=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””><a>a href=”#footnote_2890_123″ id=”identifier_2890_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>otnote_2884_123″ id=”identifier_2884_123″ class=”footnote-link footnote-identifier-link” title=””>note_2882_123″ id=”identifier_2882_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>href=”#footnote_2872_123″ id=”identifier_2872_123″ class=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_2868_123″ id=”identifier_2868_123″ class=”footnote-link footnote-identifier-link” title=””>lass=”footnote-link footnote-identifier-link” title=””>d=”identifier_2864_123″ class=”footnote-link footnote-identifier-link” title=””>ote_2862_123″ id=”identifier_2862_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_2860_123″ class=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>lass=”footnote-link footnote-identifier-link” title=””>href=”#footnote_2854_123″ id=”identifier_2854_123″ class=”footnote-link footnote-identifier-link” title=””>otnote_2852_123″ id=”identifier_2852_123″ class=”footnote-link footnote-identifier-link” title=””>ote_2850_123″ id=”identifier_2850_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_2848_123″ id=”identifier_2848_123″ class=”footnote-link footnote-identifier-link” title=””>note_2846_123″ id=”identifier_2846_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_2840_123″ id=”identifier_2840_123″ class=”footnote-link footnote-identifier-link” title=””>note_2838_123″ id=”identifier_2838_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>f=”#footnote_2834_123″ id=”identifier_2834_123″ class=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_2832_123″ id=”identifier_2832_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_2830_123″ id=”identifier_2830_123″ class=”footnote-link footnote-identifier-link” title=””>note_2828_123″ id=”identifier_2828_123″ class=”footnote-link footnote-identifier-link” title=””>ote_2826_123″ id=”identifier_2826_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_2824_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_2822_123″ id=”identifier_2822_123″ class=”footnote-link footnote-identifier-link” title=””>=”#footnote_2820_123″ id=”identifier_2820_123″ class=”footnote-link footnote-identifier-link” title=””>otnote_2818_123″ id=”identifier_2818_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_2816_123″ id=”identifier_2816_123″ class=”footnote-link footnote-identifier-link” title=””>ote_2814_123″ id=”identifier_2814_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_2812_123″ id=”identifier_2812_123″ class=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_2808_123″ id=”identifier_2808_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_2806_123″ id=”identifier_2806_123″ class=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_2800_123″ id=”identifier_2800_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_2798_123″ id=”identifier_2798_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_2796_123″ id=”identifier_2796_123″ class=”footnote-link footnote-identifier-link” title=””>ref=”#footnote_2794_123″ id=”identifier_2794_123″ class=”footnote-link footnote-identifier-link” title=””>note_2792_123″ id=”identifier_2792_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_2790_123″ id=”identifier_2790_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>=”identifier_2786_123″ class=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_2784_123″ id=”identifier_2784_123″ class=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_2782_123″ id=”identifier_2782_123″ class=”footnote-link footnote-identifier-link” title=””>otnote_2778_123″ id=”identifier_2778_123″ class=”footnote-link footnote-identifier-link” title=””>note_2776_123″ id=”identifier_2776_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_2774_123″ id=”identifier_2774_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_2766_123″ id=”identifier_2766_123″ class=”footnote-link footnote-identifier-link” title=””>lass=”footnote-link footnote-identifier-link” title=””>d=”identifier_2762_123″ class=”footnote-link footnote-identifier-link” title=””>=”#footnote_2760_123″ id=”identifier_2760_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_2758_123″ class=”footnote-link footnote-identifier-link” title=””>lass=”footnote-link footnote-identifier-link” title=””>f=”#footnote_2754_123″ id=”identifier_2754_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>href=”#footnote_2748_123″ id=”identifier_2748_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_2746_123″ id=”identifier_2746_123″ class=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_2742_123″ id=”identifier_2742_123″ class=”footnote-link footnote-identifier-link” title=””>ref=”#footnote_2740_123″ id=”identifier_2740_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_2738_123″ id=”identifier_2738_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_2730_123″ id=”identifier_2730_123″ class=”footnote-link footnote-identifier-link” title=””>=”identifier_2726_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_2724_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_2720_123″ class=”footnote-link footnote-identifier-link” title=””>=”identifier_2718_123″ class=”footnote-link footnote-identifier-link” title=””>ote_2716_123″ id=”identifier_2716_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_2714_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_2712_123″ id=”identifier_2712_123″ class=”footnote-link footnote-identifier-link” title=””>lass=”footnote-link footnote-identifier-link” title=””>d=”identifier_2708_123″ class=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_2704_123″ id=”identifier_2704_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_2702_123″ id=”identifier_2702_123″ class=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_2696_123″ id=”identifier_2696_123″ class=”footnote-link footnote-identifier-link” title=””>link footnote-identifier-link” title=””>ote_2692_123″ id=”identifier_2692_123″ class=”footnote-link footnote-identifier-link” title=””>otnote_2690_123″ id=”identifier_2690_123″ class=”footnote-link footnote-identifier-link” title=””>ote_2688_123″ id=”identifier_2688_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_2686_123″ id=”identifier_2686_123″ class=”footnote-link footnote-identifier-link” title=””>=”identifier_2684_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_2682_123″ id=”identifier_2682_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_2678_123″ class=”footnote-link footnote-identifier-link” title=””>note_2676_123″ id=”identifier_2676_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_2674_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>ote_2670_123″ id=”identifier_2670_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_2668_123″ id=”identifier_2668_123″ class=”footnote-link footnote-identifier-link” title=””>“>“>t;”>d=”identifier_2662_123″ class=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>a href=”#footnote_2658_123″ id=”identifier_2658_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_2654_123″ id=”identifier_2654_123″ class=”footnote-link footnote-identifier-link” title=””>“>“>“>“>“>“>“>ot;”>#footnote_2646_123″ id=”identifier_2646_123″ class=”footnote-link footnote-identifier-link” title=””>note_2644_123″ id=”identifier_2644_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>d=”identifier_2640_123″ class=”footnote-link footnote-identifier-link” title=””>=”identifier_2636_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_2634_123″ id=”identifier_2634_123″ class=”footnote-link footnote-identifier-link” title=””>note_2632_123″ id=”identifier_2632_123″ class=”footnote-link footnote-identifier-link” title=””>ote_2630_123″ id=”identifier_2630_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_2628_123″ id=”identifier_2628_123″ class=”footnote-link footnote-identifier-link” title=””>=”identifier_2626_123″ class=”footnote-link footnote-identifier-link” title=””>ote_2624_123″ id=”identifier_2624_123″ class=”footnote-link footnote-identifier-link” title=””>ote_2620_123″ id=”identifier_2620_123″ class=”footnote-link footnote-identifier-link” title=””>ot;”>#footnote_2616_123″ id=”identifier_2616_123″ class=”footnote-link footnote-identifier-link” title=””>“#footnote_2614_123″ id=”identifier_2614_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_2608_123″ id=”identifier_2608_123″ class=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>lass=”footnote-link footnote-identifier-link” title=””>href=”#footnote_2602_123″ id=”identifier_2602_123″ class=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>a href=”#footnote_2596_123″ id=”identifier_2596_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>otnote_2586_123″ id=”identifier_2586_123″ class=”footnote-link footnote-identifier-link” title=””>note_2584_123″ id=”identifier_2584_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>href=”#footnote_2574_123″ id=”identifier_2574_123″ class=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_2570_123″ id=”identifier_2570_123″ class=”footnote-link footnote-identifier-link” title=””>lass=”footnote-link footnote-identifier-link” title=””>d=”identifier_2566_123″ class=”footnote-link footnote-identifier-link” title=””>ote_2564_123″ id=”identifier_2564_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_2562_123″ class=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>lass=”footnote-link footnote-identifier-link” title=””>href=”#footnote_2556_123″ id=”identifier_2556_123″ class=”footnote-link footnote-identifier-link” title=””>=”identifier_2554_123″ class=”footnote-link footnote-identifier-link” title=””>ote_2552_123″ id=”identifier_2552_123″ class=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_2550_123″ id=”identifier_2550_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_2548_123″ id=”identifier_2548_123″ class=”footnote-link footnote-identifier-link” title=””>note_2546_123″ id=”identifier_2546_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>f=”#footnote_2542_123″ id=”identifier_2542_123″ class=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_2540_123″ id=”identifier_2540_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_2538_123″ id=”identifier_2538_123″ class=”footnote-link footnote-identifier-link” title=””>note_2536_123″ id=”identifier_2536_123″ class=”footnote-link footnote-identifier-link” title=””>ote_2534_123″ id=”identifier_2534_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_2532_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_2530_123″ id=”identifier_2530_123″ class=”footnote-link footnote-identifier-link” title=””>=”#footnote_2528_123″ id=”identifier_2528_123″ class=”footnote-link footnote-identifier-link” title=””>otnote_2526_123″ id=”identifier_2526_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_2524_123″ id=”identifier_2524_123″ class=”footnote-link footnote-identifier-link” title=””>ote_2522_123″ id=”identifier_2522_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_2520_123″ id=”identifier_2520_123″ class=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_2516_123″ id=”identifier_2516_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_2514_123″ id=”identifier_2514_123″ class=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_2508_123″ id=”identifier_2508_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_2506_123″ id=”identifier_2506_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_2504_123″ id=”identifier_2504_123″ class=”footnote-link footnote-identifier-link” title=””>ref=”#footnote_2502_123″ id=”identifier_2502_123″ class=”footnote-link footnote-identifier-link” title=””>note_2500_123″ id=”identifier_2500_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_2498_123″ id=”identifier_2498_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>=”identifier_2494_123″ class=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_2492_123″ id=”identifier_2492_123″ class=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_2490_123″ id=”identifier_2490_123″ class=”footnote-link footnote-identifier-link” title=””>otnote_2486_123″ id=”identifier_2486_123″ class=”footnote-link footnote-identifier-link” title=””>note_2484_123″ id=”identifier_2484_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_2482_123″ id=”identifier_2482_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_2474_123″ id=”identifier_2474_123″ class=”footnote-link footnote-identifier-link” title=””>lass=”footnote-link footnote-identifier-link” title=””>d=”identifier_2470_123″ class=”footnote-link footnote-identifier-link” title=””>=”#footnote_2468_123″ id=”identifier_2468_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_2466_123″ class=”footnote-link footnote-identifier-link” title=””>lass=”footnote-link footnote-identifier-link” title=””>f=”#footnote_2462_123″ id=”identifier_2462_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>href=”#footnote_2456_123″ id=”identifier_2456_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_2454_123″ id=”identifier_2454_123″ class=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_2450_123″ id=”identifier_2450_123″ class=”footnote-link footnote-identifier-link” title=””>ref=”#footnote_2448_123″ id=”identifier_2448_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_2446_123″ id=”identifier_2446_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_2438_123″ id=”identifier_2438_123″ class=”footnote-link footnote-identifier-link” title=””>=”identifier_2434_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_2432_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_2428_123″ class=”footnote-link footnote-identifier-link” title=””>=”identifier_2426_123″ class=”footnote-link footnote-identifier-link” title=””>ote_2424_123″ id=”identifier_2424_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_2422_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_2420_123″ id=”identifier_2420_123″ class=”footnote-link footnote-identifier-link” title=””>lass=”footnote-link footnote-identifier-link” title=””>d=”identifier_2416_123″ class=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_2412_123″ id=”identifier_2412_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_2410_123″ id=”identifier_2410_123″ class=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>23″ id=”identifier_2386_123″ class=”footnote-link footnote-identifier-link” title=””>link footnote-identifier-link” title=””>82_123″ id=”identifier_2382_123″ class=”footnote-link footnote-identifier-link” title=””>“>_123″ id=”identifier_2380_123″ class=”footnote-link footnote-identifier-link” title=””>23″ id=”identifier_2378_123″ class=”footnote-link footnote-identifier-link” title=””>23″ id=”identifier_2376_123″ class=”footnote-link footnote-identifier-link” title=””>0_123″ id=”identifier_2370_123″ class=”footnote-link footnote-identifier-link” title=””>64_123″ id=”identifier_2364_123″ class=”footnote-link footnote-identifier-link” title=””>354_123″ id=”identifier_2354_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_2352_123″ id=”identifier_2352_123″ class=”footnote-link footnote-identifier-link” title=””>“>_123″ id=”identifier_2357_123″ class=”footnote-link footnote-identifier-link” title=”“>_123″ id=”identifier_2350_123″ class=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_2346_123″ id=”identifier_2346_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_2344_123″ id=”identifier_2344_123″ class=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link 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title=””>ass=”footnote-link footnote-identifier-link” title=””>otnote_2298_123″ id=”identifier_2298_123″ class=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>otnote_2292_123″ id=”identifier_2292_123″ class=”footnote-link footnote-identifier-link” title=””>ote_2290_123″ id=”identifier_2290_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_2282_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_2280_123″ id=”identifier_2280_123″ class=”footnote-link footnote-identifier-link” title=””>lass=”footnote-link footnote-identifier-link” title=””>d=”identifier_2276_123″ class=”footnote-link footnote-identifier-link” title=””>=”#footnote_2274_123″ id=”identifier_2274_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_2272_123″ class=”footnote-link footnote-identifier-link” title=””>lass=”footnote-link footnote-identifier-link” title=””>f=”#footnote_2268_123″ id=”identifier_2268_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>href=”#footnote_2262_123″ id=”identifier_2262_123″ class=”footnote-link footnote-identifier-link” title=””>=”#footnote_2260_123″ id=”identifier_2260_123″ class=”footnote-link footnote-identifier-link” title=””>otnote_2258_123″ id=”identifier_2258_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_2256_123″ id=”identifier_2256_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>f=”#footnote_2250_123″ id=”identifier_2250_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_2246_123″ id=”identifier_2246_123″ class=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>href=”#footnote_2242_123″ id=”identifier_2242_123″ class=”footnote-link footnote-identifier-link” title=””>ref=”#footnote_2240_123″ id=”identifier_2240_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_2236_123″ class=”footnote-link footnote-identifier-link” title=””>ref=”#footnote_2234_123″ id=”identifier_2234_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_2232_123″ id=”identifier_2232_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_2226_123″ id=”identifier_2226_123″ class=”footnote-link footnote-identifier-link” title=””>=”identifier_2224_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_2222_123″ id=”identifier_2222_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_2218_123″ class=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_2216_123″ id=”identifier_2216_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_2214_123″ id=”identifier_2214_123″ class=”footnote-link footnote-identifier-link” title=””>note_2212_123″ id=”identifier_2212_123″ class=”footnote-link footnote-identifier-link” title=””>lass=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_2208_123″ id=”identifier_2208_123″ class=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_2206_123″ id=”identifier_2206_123″ class=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_2204_123″ id=”identifier_2204_123″ class=”footnote-link footnote-identifier-link” title=””>ref=”#footnote_2202_123″ id=”identifier_2202_123″ class=”footnote-link footnote-identifier-link” title=””>lass=”footnote-link footnote-identifier-link” title=””>href=”#footnote_2198_123″ id=”identifier_2198_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>d=”identifier_2194_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_2192_123″ id=”identifier_2192_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_2186_123″ id=”identifier_2186_123″ class=”footnote-link footnote-identifier-link” title=””>=”identifier_2182_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_2180_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_2176_123″ class=”footnote-link footnote-identifier-link” title=””>=”identifier_2174_123″ class=”footnote-link footnote-identifier-link” title=””>ote_2172_123″ id=”identifier_2172_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_2170_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_2168_123″ id=”identifier_2168_123″ class=”footnote-link footnote-identifier-link” title=””>lass=”footnote-link footnote-identifier-link” title=””>d=”identifier_2164_123″ class=”footnote-link footnote-identifier-link” title=””>otnote_2160_123″ id=”identifier_2160_123″ class=”footnote-link footnote-identifier-link” title=””>note_2158_123″ id=”identifier_2158_123″ class=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_2156_123″ id=”identifier_2156_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_2154_123″ id=”identifier_2154_123″ class=”footnote-link footnote-identifier-link” title=””>ote_2152_123″ id=”identifier_2152_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_2150_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_2148_123″ id=”identifier_2148_123″ class=”footnote-link footnote-identifier-link” title=””> footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>d=”identifier_2142_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_2138_123″ id=”identifier_2138_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>otnote_2130_123″ id=”identifier_2130_123″ class=”footnote-link footnote-identifier-link” title=””>lass=”footnote-link footnote-identifier-link” title=””>href=”#footnote_2126_123″ id=”identifier_2126_123″ class=”footnote-link footnote-identifier-link” title=””>otnote_2124_123″ id=”identifier_2124_123″ class=”footnote-link footnote-identifier-link” title=””>note_2122_123″ id=”identifier_2122_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_2120_123″ id=”identifier_2120_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_2118_123″ id=”identifier_2118_123″ class=”footnote-link footnote-identifier-link” title=””>lass=”footnote-link footnote-identifier-link” title=””>ote_2114_123″ id=”identifier_2114_123″ class=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_2112_123″ id=”identifier_2112_123″ class=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_2110_123″ id=”identifier_2110_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_2108_123″ id=”identifier_2108_123″ class=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>otnote_2104_123″ id=”identifier_2104_123″ class=”footnote-link footnote-identifier-link” title=””>note_2102_123″ id=”identifier_2102_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_2100_123″ id=”identifier_2100_123″ class=”footnote-link footnote-identifier-link” title=””>=”#footnote_2098_123″ id=”identifier_2098_123″ class=”footnote-link footnote-identifier-link” title=””>otnote_2096_123″ id=”identifier_2096_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_2094_123″ id=”identifier_2094_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_2092_123″ id=”identifier_2092_123″ class=”footnote-link footnote-identifier-link” title=””>lass=”footnote-link footnote-identifier-link” title=””>ote_2088_123″ id=”identifier_2088_123″ class=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_2086_123″ id=”identifier_2086_123″ class=”footnote-link footnote-identifier-link” title=””>ote_2084_123″ id=”identifier_2084_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_2082_123″ id=”identifier_2082_123″ class=”footnote-link footnote-identifier-link” title=””>note_2080_123″ id=”identifier_2080_123″ class=”footnote-link footnote-identifier-link” title=””>ote_2078_123″ id=”identifier_2078_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_2076_123″ class=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_2074_123″ id=”identifier_2074_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_2070_123″ id=”identifier_2070_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_2064_123″ id=”identifier_2064_123″ class=”footnote-link footnote-identifier-link” title=””>ote_2062_123″ id=”identifier_2062_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_2060_123″ id=”identifier_2060_123″ class=”footnote-link footnote-identifier-link” title=””>=”#footnote_2058_123″ id=”identifier_2058_123″ class=”footnote-link footnote-identifier-link” title=””>=”#footnote_2056_123″ id=”identifier_2056_123″ class=”footnote-link footnote-identifier-link” title=””>otnote_2054_123″ id=”identifier_2054_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_2050_123″ id=”identifier_2050_123″ class=”footnote-link footnote-identifier-link” title=””>ote_2048_123″ id=”identifier_2048_123″ class=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_2046_123″ id=”identifier_2046_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_2042_123″ id=”identifier_2042_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_2034_123″ id=”identifier_2034_123″ class=”footnote-link footnote-identifier-link” title=””>note_2032_123″ id=”identifier_2032_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>ote_2024_123″ id=”identifier_2024_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_2020_123″ id=”identifier_2020_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_2012_123″ id=”identifier_2012_123″ class=”footnote-link footnote-identifier-link” title=””>ote_2010_123″ id=”identifier_2010_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_2008_123″ id=”identifier_2008_123″ class=”footnote-link footnote-identifier-link” title=””>otnote_2004_123″ id=”identifier_2004_123″ class=”footnote-link footnote-identifier-link” title=””>otnote_2002_123″ id=”identifier_2002_123″ class=”footnote-link footnote-identifier-link” title=””>link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>f=”#footnote_1994_123″ id=”identifier_1994_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_1992_123″ id=”identifier_1992_123″ class=”footnote-link footnote-identifier-link” title=””>ote_1988_123″ id=”identifier_1988_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_1984_123″ class=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_1980_123″ id=”identifier_1980_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1976_123″ id=”identifier_1976_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1970_123″ id=”identifier_1970_123″ class=”footnote-link footnote-identifier-link” title=””>ote_1968_123″ id=”identifier_1968_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_1966_123″ id=”identifier_1966_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_1960_123″ id=”identifier_1960_123″ class=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_1958_123″ id=”identifier_1958_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1954_123″ id=”identifier_1954_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1946_123″ id=”identifier_1946_123″ class=”footnote-link footnote-identifier-link” title=””>ote_1944_123″ id=”identifier_1944_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_1942_123″ id=”identifier_1942_123″ class=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_1938_123″ id=”identifier_1938_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_1936_123″ id=”identifier_1936_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_1934_123″ id=”identifier_1934_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1930_123″ id=”identifier_1930_123″ class=”footnote-link footnote-identifier-link” title=””>ote_1928_123″ id=”identifier_1928_123″ class=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_1926_123″ id=”identifier_1926_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1922_123″ id=”identifier_1922_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1914_123″ id=”identifier_1914_123″ class=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>otnote_1910_123″ id=”identifier_1910_123″ class=”footnote-link footnote-identifier-link” title=””>ote_1908_123″ id=”identifier_1908_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1904_123″ id=”identifier_1904_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1898_123″ id=”identifier_1898_123″ class=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_1896_123″ id=”identifier_1896_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_1894_123″ id=”identifier_1894_123″ class=”footnote-link footnote-identifier-link” title=””>note_1892_123″ id=”identifier_1892_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_1890_123″ class=”footnote-link footnote-identifier-link” title=””>“>“>“>“>“>t“>s=”footnote-link footnote-identifier-link” title=””><a>a href=”#footnote_1870_123″ id=”identifier_1870_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>a href=”#footnote_1858_123″ id=”identifier_1858_123″ class=”footnote-link footnote-identifier-link” title=””>85_123″ id=”identifier_1850_123″ class=”footnote-link footnote-identifier-link” title=””>link footnote-identifier-link” title=””>” id=”identifier_1846_123″ class=”footnote-link footnote-identifier-link” title=””>” id=”identifier_1842_123″ class=”footnote-link footnote-identifier-link” title=””>_123″ id=”identifier_1840_123″ class=”footnote-link footnote-identifier-link” title=””>6_123″ id=”identifier_1836_123″ class=”footnote-link footnote-identifier-link” title=””>0_123″ id=”identifier_1830_123″ class=”footnote-link footnote-identifier-link” title=””>“>_123″ id=”identifier_1826_123″ class=”footnote-link footnote-identifier-link” title=””>“>_123″ id=”identifier_1820_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1818_123″ id=”identifier_1818_123″ class=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_1812_123″ id=”identifier_1812_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_1810_123″ id=”identifier_1810_123″ class=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1802_123″ id=”identifier_1802_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1794_123″ id=”identifier_1794_123″ class=”footnote-link footnote-identifier-link” title=””>ote_1792_123″ id=”identifier_1792_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_1790_123″ class=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1784_123″ id=”identifier_1784_123″ class=”footnote-link footnote-identifier-link” title=””>ote_1780_123″ id=”identifier_1780_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_1778_123″ id=”identifier_1778_123″ class=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_1776_123″ id=”identifier_1776_123″ class=”footnote-link footnote-identifier-link” title=””>=”identifier_1774_123″ class=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>d=”identifier_1770_123″ class=”footnote-link footnote-identifier-link” title=””>ref=”#footnote_1768_123″ id=”identifier_1768_123″ class=”footnote-link footnote-identifier-link” title=””>lass=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1764_123″ id=”identifier_1764_123″ class=”footnote-link footnote-identifier-link” title=””>lass=”footnote-link footnote-identifier-link” title=””>d=”identifier_1760_123″ class=”footnote-link footnote-identifier-link” title=””>otnote_1756_123″ id=”identifier_1756_123″ class=”footnote-link footnote-identifier-link” title=””>note_1754_123″ id=”identifier_1754_123″ class=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_1752_123″ id=”identifier_1752_123″ class=”footnote-link footnote-identifier-link” title=””>link footnote-identifier-link” title=””>ote_1748_123″ id=”identifier_1748_123″ class=”footnote-link footnote-identifier-link” title=””>otnote_1746_123″ id=”identifier_1746_123″ class=”footnote-link footnote-identifier-link” title=””>ote_1744_123″ id=”identifier_1744_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1742_123″ id=”identifier_1742_123″ class=”footnote-link footnote-identifier-link” title=””>=”identifier_1740_123″ class=”footnote-link footnote-identifier-link” title=””>ote_1738_123″ id=”identifier_1738_123″ class=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_1736_123″ id=”identifier_1736_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1734_123″ id=”identifier_1734_123″ class=”footnote-link footnote-identifier-link” title=””>lass=”footnote-link footnote-identifier-link” title=””>d=”identifier_1730_123″ class=”footnote-link footnote-identifier-link” title=””>otnote_1726_123″ id=”identifier_1726_123″ class=”footnote-link footnote-identifier-link” title=””>note_1724_123″ id=”identifier_1724_123″ class=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_1722_123″ id=”identifier_1722_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1720_123″ id=”identifier_1720_123″ class=”footnote-link footnote-identifier-link” title=””>lass=”footnote-link footnote-identifier-link” title=””>d=”identifier_1714_123″ class=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_1710_123″ id=”identifier_1710_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_1708_123″ id=”identifier_1708_123″ class=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_1702_123″ id=”identifier_1702_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1700_123″ id=”identifier_1700_123″ class=”footnote-link footnote-identifier-link” title=””> footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>d=”identifier_1694_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1690_123″ id=”identifier_1690_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>otnote_1682_123″ id=”identifier_1682_123″ class=”footnote-link footnote-identifier-link” title=””>lass=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1678_123″ id=”identifier_1678_123″ class=”footnote-link footnote-identifier-link” title=””>ote_1676_123″ id=”identifier_1676_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_1674_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1672_123″ id=”identifier_1672_123″ class=”footnote-link footnote-identifier-link” title=””>ote_1670_123″ id=”identifier_1670_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_1668_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_1666_123″ id=”identifier_1666_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_1662_123″ id=”identifier_1662_123″ class=”footnote-link footnote-identifier-link” title=””>lass=”footnote-link footnote-identifier-link” title=””>link footnote-identifier-link” title=””>656_123″ id=”identifier_1656_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_1652_123″ id=”identifier_1652_123″ class=”footnote-link footnote-identifier-link” title=””>ref=”#footnote_1650_123″ id=”identifier_1650_123″ class=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_1644_123″ id=”identifier_1644_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1642_123″ id=”identifier_1642_123″ class=”footnote-link footnote-identifier-link” title=””>ote_1640_123″ id=”identifier_1640_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_1638_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1636_123″ id=”identifier_1636_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>f=”#footnote_1632_123″ id=”identifier_1632_123″ class=”footnote-link footnote-identifier-link” title=””>otnote_1628_123″ id=”identifier_1628_123″ class=”footnote-link footnote-identifier-link” title=””>note_1626_123″ id=”identifier_1626_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_1624_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_1620_123″ id=”identifier_1620_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1618_123″ id=”identifier_1618_123″ class=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>f=”#footnote_1612_123″ id=”identifier_1612_123″ class=”footnote-link footnote-identifier-link” title=””>lass=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1608_123″ id=”identifier_1608_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1604_123″ id=”identifier_1604_123″ class=”footnote-link footnote-identifier-link” title=””>=”#footnote_1602_123″ id=”identifier_1602_123″ class=”footnote-link footnote-identifier-link” title=””>otnote_1600_123″ id=”identifier_1600_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1598_123″ id=”identifier_1598_123″ class=”footnote-link footnote-identifier-link” title=””>ote_1596_123″ id=”identifier_1596_123″ class=”footnote-link footnote-identifier-link” title=””>otnote_1594_123″ id=”identifier_1594_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_1592_123″ class=”footnote-link footnote-identifier-link” title=””>note_1590_123″ id=”identifier_1590_123″ class=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_1588_123″ id=”identifier_1588_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_1584_123″ class=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_1582_123″ id=”identifier_1582_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_1580_123″ id=”identifier_1580_123″ class=”footnote-link footnote-identifier-link” title=””>note_1578_123″ id=”identifier_1578_123″ class=”footnote-link footnote-identifier-link” title=””>lass=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_1574_123″ id=”identifier_1574_123″ class=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_1572_123″ id=”identifier_1572_123″ class=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_1570_123″ id=”identifier_1570_123″ class=”footnote-link footnote-identifier-link” title=””>ref=”#footnote_1568_123″ id=”identifier_1568_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1564_123″ id=”identifier_1564_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1558_123″ id=”identifier_1558_123″ class=”footnote-link footnote-identifier-link” title=””>ote_1556_123″ id=”identifier_1556_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_1554_123″ id=”identifier_1554_123″ class=”footnote-link footnote-identifier-link” title=””>=”#footnote_1552_123″ id=”identifier_1552_123″ class=”footnote-link footnote-identifier-link” title=””>=”#footnote_1550_123″ id=”identifier_1550_123″ class=”footnote-link footnote-identifier-link” title=””>otnote_1548_123″ id=”identifier_1548_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1544_123″ id=”identifier_1544_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1536_123″ id=”identifier_1536_123″ class=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>otnote_1532_123″ id=”identifier_1532_123″ class=”footnote-link footnote-identifier-link” title=””>ote_1530_123″ id=”identifier_1530_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1526_123″ id=”identifier_1526_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1518_123″ id=”identifier_1518_123″ class=”footnote-link footnote-identifier-link” title=””>ote_1516_123″ id=”identifier_1516_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_1514_123″ id=”identifier_1514_123″ class=”footnote-link footnote-identifier-link” title=””>otnote_1510_123″ id=”identifier_1510_123″ class=”footnote-link footnote-identifier-link” title=””>otnote_1508_123″ id=”identifier_1508_123″ class=”footnote-link footnote-identifier-link” title=””>link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>f=”#footnote_1500_123″ id=”identifier_1500_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_1498_123″ id=”identifier_1498_123″ class=”footnote-link footnote-identifier-link” title=””>ote_1494_123″ id=”identifier_1494_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_1490_123″ class=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_1486_123″ id=”identifier_1486_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1482_123″ id=”identifier_1482_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1476_123″ id=”identifier_1476_123″ class=”footnote-link footnote-identifier-link” title=””>ote_1474_123″ id=”identifier_1474_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_1472_123″ id=”identifier_1472_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_1466_123″ id=”identifier_1466_123″ class=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_1464_123″ id=”identifier_1464_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1460_123″ id=”identifier_1460_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1454_123″ id=”identifier_1454_123″ class=”footnote-link footnote-identifier-link” title=””>note_1452_123″ id=”identifier_1452_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_1450_123″ id=”identifier_1450_123″ class=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_1446_123″ id=”identifier_1446_123″ class=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_1444_123″ id=”identifier_1444_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1438_123″ id=”identifier_1438_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1432_123″ id=”identifier_1432_123″ class=”footnote-link footnote-identifier-link” title=””>note_1430_123″ id=”identifier_1430_123″ class=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_1428_123″ id=”identifier_1428_123″ class=”footnote-link footnote-identifier-link” title=””>otnote_1426_123″ id=”identifier_1426_123″ class=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_1418_123″ id=”identifier_1418_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1414_123″ id=”identifier_1414_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1408_123″ id=”identifier_1408_123″ class=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_1406_123″ id=”identifier_1406_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_1404_123″ id=”identifier_1404_123″ class=”footnote-link footnote-identifier-link” title=””>note_1402_123″ id=”identifier_1402_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_1400_123″ class=”footnote-link footnote-identifier-link” title=””>“>“>t“>s=”footnote-link footnote-identifier-link” title=””><a>a href=”#footnote_1380_123″ id=”identifier_1380_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>a href=”#footnote_1368_123″ id=”identifier_1368_123″ class=”footnote-link footnote-identifier-link” title=””>link footnote-identifier-link” title=””>_123″ id=”identifier_1359_123″ class=”footnote-link footnote-identifier-link” title=”2″>3″ id=”identifier_1358_123″ class=”footnote-link footnote-identifier-link” title=””>56_123″ id=”identifier_1356_123″ class=”footnote-link footnote-identifier-link” title=””>_123″ id=”identifier_1349_123″ class=”footnote-link footnote-identifier-link” title=”5″>_123″ id=”identifier_1345_123″ class=”footnote-link footnote-identifier-link” title=”3″>44_123″ id=”identifier_1344_123″ class=”footnote-link footnote-identifier-link” title=””>342_123″ id=”identifier_1342_123″ class=”footnote-link footnote-identifier-link” title=””>340_123″ id=”identifier_1340_123″ class=”footnote-link footnote-identifier-link” title=””>_123″ id=”identifier_1334_123″ class=”footnote-link footnote-identifier-link” title=””>“>_13″ id=”identifier_1330_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1328_123″ id=”identifier_1328_123″ class=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>otnote_1324_123″ id=”identifier_1324_123″ class=”footnote-link footnote-identifier-link” title=””>ote_1322_123″ id=”identifier_1322_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1312_123″ id=”identifier_1312_123″ class=”footnote-link footnote-identifier-link” title=””>ote_1310_123″ id=”identifier_1310_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_1308_123″ class=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1302_123″ id=”identifier_1302_123″ class=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_1296_123″ id=”identifier_1296_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_1294_123″ id=”identifier_1294_123″ class=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1286_123″ id=”identifier_1286_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1282_123″ id=”identifier_1282_123″ class=”footnote-link footnote-identifier-link” title=””>276_123″ id=”identifier_1276_123″ class=”footnote-link footnote-identifier-link” title=””>link footnote-identifier-link” title=””>_123″ id=”identifier_1270_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1268_123″ id=”identifier_1268_123″ class=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_1266_123″ id=”identifier_1266_123″ class=”footnote-link footnote-identifier-link” title=””>otnote_1264_123″ id=”identifier_1264_123″ class=”footnote-link footnote-identifier-link” title=””>=”#footnote_1262_123″ id=”identifier_1262_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1260_123″ id=”identifier_1260_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_1258_123″ id=”identifier_1258_123″ class=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>otnote_1254_123″ id=”identifier_1254_123″ class=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_1252_123″ id=”identifier_1252_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1250_123″ id=”identifier_1250_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_1246_123″ id=”identifier_1246_123″ class=”footnote-link footnote-identifier-link” title=””> footnote-identifier-link” title=””>href=”#footnote_1242_123″ id=”identifier_1242_123″ class=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_1234_123″ id=”identifier_1234_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_1232_123″ id=”identifier_1232_123″ class=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_1226_123″ id=”identifier_1226_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1224_123″ id=”identifier_1224_123″ class=”footnote-link footnote-identifier-link” title=””> footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>d=”identifier_1218_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1214_123″ id=”identifier_1214_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>otnote_1206_123″ id=”identifier_1206_123″ class=”footnote-link footnote-identifier-link” title=””>lass=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1202_123″ id=”identifier_1202_123″ class=”footnote-link footnote-identifier-link” title=””>note_1200_123″ id=”identifier_1200_123″ class=”footnote-link footnote-identifier-link” title=””>ote_1198_123″ id=”identifier_1198_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_1196_123″ id=”identifier_1196_123″ class=”footnote-link footnote-identifier-link” title=””>note_1194_123″ id=”identifier_1194_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>d=”identifier_1190_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_1186_123″ id=”identifier_1186_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_1184_123″ id=”identifier_1184_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1180_123″ id=”identifier_1180_123″ class=”footnote-link footnote-identifier-link” title=””>note_1178_123″ id=”identifier_1178_123″ class=”footnote-link footnote-identifier-link” title=””>otnote_1174_123″ id=”identifier_1174_123″ class=”footnote-link footnote-identifier-link” title=””>ref=”#footnote_1172_123″ id=”identifier_1172_123″ class=”footnote-link footnote-identifier-link” title=””>note_1170_123″ id=”identifier_1170_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_1168_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1164_123″ id=”identifier_1164_123″ class=”footnote-link footnote-identifier-link” title=””>=”identifier_1162_123″ class=”footnote-link footnote-identifier-link” title=””>ote_1160_123″ id=”identifier_1160_123″ class=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_1158_123″ id=”identifier_1158_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1156_123″ id=”identifier_1156_123″ class=”footnote-link footnote-identifier-link” title=””>ref=”#footnote_1154_123″ id=”identifier_1154_123″ class=”footnote-link footnote-identifier-link” title=””>note_1152_123″ id=”identifier_1152_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_1150_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1146_123″ id=”identifier_1146_123″ class=”footnote-link footnote-identifier-link” title=””>ote_1144_123″ id=”identifier_1144_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_1142_123″ id=”identifier_1142_123″ class=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_1140_123″ id=”identifier_1140_123″ class=”footnote-link footnote-identifier-link” title=””>=”identifier_1138_123″ class=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>d=”identifier_1134_123″ class=”footnote-link footnote-identifier-link” title=””>ref=”#footnote_1132_123″ id=”identifier_1132_123″ class=”footnote-link footnote-identifier-link” title=””>lass=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1128_123″ id=”identifier_1128_123″ class=”footnote-link footnote-identifier-link” title=””>=”#footnote_1126_123″ id=”identifier_1126_123″ class=”footnote-link footnote-identifier-link” title=””>otnote_1124_123″ id=”identifier_1124_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1122_123″ id=”identifier_1122_123″ class=”footnote-link footnote-identifier-link” title=””>note_1118_123″ id=”identifier_1118_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_1116_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_1112_123″ class=”footnote-link footnote-identifier-link” title=””>note_1110_123″ id=”identifier_1110_123″ class=”footnote-link footnote-identifier-link” title=””>lass=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_1106_123″ id=”identifier_1106_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_1104_123″ id=”identifier_1104_123″ class=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_1102_123″ id=”identifier_1102_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1100_123″ id=”identifier_1100_123″ class=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>f=”#footnote_1094_123″ id=”identifier_1094_123″ class=”footnote-link footnote-identifier-link” title=””>lass=”footnote-link footnote-identifier-link” title=””>link footnote-identifier-link” title=””>href=”#footnote_1086_123″ id=”identifier_1086_123″ class=”footnote-link footnote-identifier-link” title=””>lass=”footnote-link footnote-identifier-link” title=””>d=”identifier_1082_123″ class=”footnote-link footnote-identifier-link” title=””>=”#footnote_1080_123″ id=”identifier_1080_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_1078_123″ class=”footnote-link footnote-identifier-link” title=””>lass=”footnote-link footnote-identifier-link” title=””>f=”#footnote_1074_123″ id=”identifier_1074_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>link footnote-identifier-link” title=””> footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>d=”identifier_1062_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1058_123″ id=”identifier_1058_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>otnote_1050_123″ id=”identifier_1050_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1046_123″ id=”identifier_1046_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1040_123″ id=”identifier_1040_123″ class=”footnote-link footnote-identifier-link” title=””>ote_1038_123″ id=”identifier_1038_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_1036_123″ id=”identifier_1036_123″ class=”footnote-link footnote-identifier-link” title=””>=”#footnote_1034_123″ id=”identifier_1034_123″ class=”footnote-link footnote-identifier-link” title=””>=”#footnote_1032_123″ id=”identifier_1032_123″ class=”footnote-link footnote-identifier-link” title=””>otnote_1030_123″ id=”identifier_1030_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1026_123″ id=”identifier_1026_123″ class=”footnote-link footnote-identifier-link” title=””>ote_1024_123″ id=”identifier_1024_123″ class=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_1022_123″ id=”identifier_1022_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1018_123″ id=”identifier_1018_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1010_123″ id=”identifier_1010_123″ class=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>otnote_1006_123″ id=”identifier_1006_123″ class=”footnote-link footnote-identifier-link” title=””>ote_1004_123″ id=”identifier_1004_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_1000_123″ id=”identifier_1000_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_994_123″ id=”identifier_994_123″ class=”footnote-link footnote-identifier-link” title=””>ote_992_123″ id=”identifier_992_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_990_123″ id=”identifier_990_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_984_123″ id=”identifier_984_123″ class=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_982_123″ id=”identifier_982_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_978_123″ id=”identifier_978_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_970_123″ id=”identifier_970_123″ class=”footnote-link footnote-identifier-link” title=””>ote_968_123″ id=”identifier_968_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_966_123″ id=”identifier_966_123″ class=”footnote-link footnote-identifier-link” title=””>otnote_962_123″ id=”identifier_962_123″ class=”footnote-link footnote-identifier-link” title=””>otnote_960_123″ id=”identifier_960_123″ class=”footnote-link footnote-identifier-link” title=””>link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>f=”#footnote_952_123″ id=”identifier_952_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_950_123″ id=”identifier_950_123″ class=”footnote-link footnote-identifier-link” title=””>ote_946_123″ id=”identifier_946_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_942_123″ class=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_938_123″ id=”identifier_938_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_934_123″ id=”identifier_934_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_926_123″ id=”identifier_926_123″ class=”footnote-link footnote-identifier-link” title=””> footnote-identifier-link” title=””>d=”identifier_920_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_916_123″ id=”identifier_916_123″ class=”footnote-link footnote-identifier-link” title=””>ote_914_123″ id=”identifier_914_123″ class=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_912_123″ id=”identifier_912_123″ class=”footnote-link footnote-identifier-link” title=””>link footnote-identifier-link” title=””>ote_906_123″ id=”identifier_906_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_904_123″ id=”identifier_904_123″ 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title=””>s=”footnote-link footnote-identifier-link” title=””>f=”#footnote_750_123″ id=”identifier_750_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>ote_746_123″ id=”identifier_746_123″ class=”footnote-link footnote-identifier-link” title=””>otnote_744_123″ id=”identifier_744_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>f=”#footnote_738_123″ id=”identifier_738_123″ class=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_736_123″ id=”identifier_736_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_734_123″ id=”identifier_734_123″ class=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>f=”#footnote_728_123″ id=”identifier_728_123″ class=”footnote-link footnote-identifier-link” title=””>lass=”footnote-link 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footnote-identifier-link” title=””>d=”identifier_594_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_592_123″ id=”identifier_592_123″ class=”footnote-link footnote-identifier-link” title=””>=”#footnote_590_123″ id=”identifier_590_123″ class=”footnote-link footnote-identifier-link” title=””>otnote_588_123″ id=”identifier_588_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_586_123″ id=”identifier_586_123″ class=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>f=”#footnote_582_123″ id=”identifier_582_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_578_123″ id=”identifier_578_123″ class=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>href=”#footnote_574_123″ id=”identifier_574_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_572_123″ id=”identifier_572_123″ 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id=”identifier_550_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>f=”#footnote_544_123″ id=”identifier_544_123″ class=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_542_123″ id=”identifier_542_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_540_123″ id=”identifier_540_123″ class=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>f=”#footnote_534_123″ id=”identifier_534_123″ class=”footnote-link footnote-identifier-link” title=””>lass=”footnote-link footnote-identifier-link” title=””>href=”#footnote_530_123″ id=”identifier_530_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_526_123″ id=”identifier_526_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_522_123″ id=”identifier_522_123″ class=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_520_123″ id=”identifier_520_123″ class=”footnote-link footnote-identifier-link” title=””>otnote_518_123″ id=”identifier_518_123″ class=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_514_123″ id=”identifier_514_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_512_123″ id=”identifier_512_123″ class=”footnote-link footnote-identifier-link” title=””>ref=”#footnote_510_123″ id=”identifier_510_123″ class=”footnote-link footnote-identifier-link” title=””>note_508_123″ id=”identifier_508_123″ class=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_506_123″ id=”identifier_506_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_500_123″ id=”identifier_500_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>ote_494_123″ id=”identifier_494_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_492_123″ id=”identifier_492_123″ class=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_488_123″ id=”identifier_488_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_486_123″ id=”identifier_486_123″ class=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_480_123″ id=”identifier_480_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_478_123″ id=”identifier_478_123″ class=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_476_123″ id=”identifier_476_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_474_123″ id=”identifier_474_123″ class=”footnote-link footnote-identifier-link” title=””>ref=”#footnote_472_123″ id=”identifier_472_123″ class=”footnote-link footnote-identifier-link” title=””>note_470_123″ id=”identifier_470_123″ class=”footnote-link footnote-identifier-link” title=””>otnote_468_123″ id=”identifier_468_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_466_123″ id=”identifier_466_123″ class=”footnote-link footnote-identifier-link” title=””>=”identifier_464_123″ class=”footnote-link footnote-identifier-link” title=””>ote_462_123″ id=”identifier_462_123″ class=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_460_123″ id=”identifier_460_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_458_123″ id=”identifier_458_123″ class=”footnote-link footnote-identifier-link” title=””>note_456_123″ id=”identifier_456_123″ class=”footnote-link footnote-identifier-link” title=””>ote_452_123″ id=”identifier_452_123″ class=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_450_123″ id=”identifier_450_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_448_123″ id=”identifier_448_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_444_123″ id=”identifier_444_123″ class=”footnote-link footnote-identifier-link” title=””> footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>d=”identifier_436_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_432_123″ id=”identifier_432_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>otnote_424_123″ id=”identifier_424_123″ class=”footnote-link footnote-identifier-link” title=””>lass=”footnote-link footnote-identifier-link” title=””>href=”#footnote_420_123″ id=”identifier_420_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>=”identifier_416_123″ class=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_414_123″ id=”identifier_414_123″ class=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_412_123″ id=”identifier_412_123″ class=”footnote-link footnote-identifier-link” title=””>otnote_408_123″ id=”identifier_408_123″ class=”footnote-link footnote-identifier-link” title=””>note_406_123″ id=”identifier_406_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_404_123″ id=”identifier_404_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>f=”#footnote_400_123″ id=”identifier_400_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>ote_396_123″ id=”identifier_396_123″ class=”footnote-link footnote-identifier-link” title=””>otnote_394_123″ id=”identifier_394_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>f=”#footnote_388_123″ id=”identifier_388_123″ class=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_386_123″ id=”identifier_386_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_384_123″ id=”identifier_384_123″ class=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>f=”#footnote_378_123″ id=”identifier_378_123″ class=”footnote-link footnote-identifier-link” title=””>lass=”footnote-link footnote-identifier-link” title=””>href=”#footnote_374_123″ id=”identifier_374_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_370_123″ id=”identifier_370_123″ class=”footnote-link footnote-identifier-link” title=””>lass=”footnote-link footnote-identifier-link” title=””>d=”identifier_366_123″ class=”footnote-link footnote-identifier-link” title=””>=”#footnote_364_123″ id=”identifier_364_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_362_123″ class=”footnote-link footnote-identifier-link” title=””>lass=”footnote-link footnote-identifier-link” title=””>f=”#footnote_358_123″ id=”identifier_358_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>link footnote-identifier-link” title=””>ote_350_123″ id=”identifier_350_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_348_123″ id=”identifier_348_123″ class=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_344_123″ id=”identifier_344_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_342_123″ id=”identifier_342_123″ class=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_336_123″ id=”identifier_336_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_334_123″ id=”identifier_334_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_332_123″ id=”identifier_332_123″ class=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_330_123″ id=”identifier_330_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_324_123″ id=”identifier_324_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_322_123″ id=”identifier_322_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_318_123″ id=”identifier_318_123″ class=”footnote-link footnote-identifier-link” title=””>otnote_316_123″ id=”identifier_316_123″ class=”footnote-link footnote-identifier-link” title=””>note_314_123″ id=”identifier_314_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_312_123″ id=”identifier_312_123″ class=”footnote-link footnote-identifier-link” title=””>link footnote-identifier-link” title=””>note_304_123″ id=”identifier_304_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_302_123″ id=”identifier_302_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>href=”#footnote_298_123″ id=”identifier_298_123″ class=”footnote-link footnote-identifier-link” title=””>ote_296_123″ id=”identifier_296_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_294_123″ id=”identifier_294_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_292_123″ id=”identifier_292_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_288_123″ id=”identifier_288_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_286_123″ id=”identifier_286_123″ class=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_282_123″ id=”identifier_282_123″ class=”footnote-link footnote-identifier-link” title=””>ref=”#footnote_280_123″ id=”identifier_280_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_278_123″ id=”identifier_278_123″ class=”footnote-link 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id=”identifier_132_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_130_123″ id=”identifier_130_123″ class=”footnote-link footnote-identifier-link” title=””>note_128_123″ id=”identifier_128_123″ class=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_126_123″ id=”identifier_126_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_124_123″ id=”identifier_124_123″ class=”footnote-link footnote-identifier-link” title=””>=”identifier_122_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_120_123″ id=”identifier_120_123″ class=”footnote-link footnote-identifier-link” title=””>note_118_123″ id=”identifier_118_123″ class=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_116_123″ id=”identifier_116_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_112_123″ class=”footnote-link footnote-identifier-link” title=””>note_110_123″ id=”identifier_110_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>f=”#footnote_106_123″ id=”identifier_106_123″ class=”footnote-link footnote-identifier-link” title=””>ote_102_123″ id=”identifier_102_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_100_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_98_123″ id=”identifier_98_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_96_123″ id=”identifier_96_123″ class=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_94_123″ id=”identifier_94_123″ class=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_92_123″ id=”identifier_92_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_90_123″ id=”identifier_90_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>ote_86_123″ id=”identifier_86_123″ class=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_84_123″ id=”identifier_84_123″ class=”footnote-link footnote-identifier-link” title=””>ref=”#footnote_78_123″ id=”identifier_78_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_76_123″ id=”identifier_76_123″ class=”footnote-link footnote-identifier-link” title=””>ote_74_123″ id=”identifier_74_123″ class=”footnote-link footnote-identifier-link” title=””>d=”identifier_72_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_70_123″ id=”identifier_70_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_68_123″ id=”identifier_68_123″ class=”footnote-link footnote-identifier-link” title=””>lass=”footnote-link footnote-identifier-link” title=””>ote_64_123″ id=”identifier_64_123″ class=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_62_123″ id=”identifier_62_123″ class=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_60_123″ id=”identifier_60_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_58_123″ id=”identifier_58_123″ class=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>otnote_54_123″ id=”identifier_54_123″ class=”footnote-link footnote-identifier-link” title=””>note_52_123″ id=”identifier_52_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_50_123″ id=”identifier_50_123″ class=”footnote-link footnote-identifier-link” title=””>=”identifier_48_123″ class=”footnote-link footnote-identifier-link” title=””>ote_46_123″ id=”identifier_46_123″ class=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_44_123″ id=”identifier_44_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_42_123″ id=”identifier_42_123″ class=”footnote-link footnote-identifier-link” title=””>ef=”#footnote_36_123″ id=”identifier_36_123″ class=”footnote-link footnote-identifier-link” title=””>f=”#footnote_34_123″ id=”identifier_34_123″ class=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>ass=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_28_123″ id=”identifier_28_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_26_123″ id=”identifier_26_123″ class=”footnote-link footnote-identifier-link” title=””>=”#footnote_24_123″ id=”identifier_24_123″ class=”footnote-link footnote-identifier-link” title=””>otnote_22_123″ id=”identifier_22_123″ class=”footnote-link footnote-identifier-link” title=””>href=”#footnote_20_123″ id=”identifier_20_123″ class=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>s=”footnote-link footnote-identifier-link” title=””>d=”identifier_12_123″ class=”footnote-link footnote-identifier-link” title=””>ote_10_123″ id=”identifier_10_123″ class=”footnote-link footnote-identifier-link” title=””>< href=”#footnote_8_123″ id=”identifier_8_123″ class=”footnote-link footnote-identifier-link” title=””>ref=”#footnote_6_123″ id=”identifier_6_123″ class=”footnote-link footnote-identifier-link” title=””>lass=”footnote-link footnote-identifier-link” title=””>f=”#footnote_2_123″ id=”identifier_2_123″ class=”footnote-link footnote-identifier-link” title=””>“>“>“>“>“>“>echanis“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>s of aller“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“> and tolerance in h“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>mans are in“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>estigated at the “>“>“>“>“>“>“> cell and “>“>“>“>“>“>“>“>“>“>“>“>“>“>“>g“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“> level“>“>“>“>“>“>“>“>“>“>“>“>“>“> “>“>“>“>“>ong-term and short-term T cell culture-systems have “>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>een set-u“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“> to measure allergen-specific T cell responses to“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>ards cow“>s milk“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“> peanut and other allergens. “>“>“>“>urthermore, “>“>“>“>“>“>“>“> cell responses at the level of immunoglobulin subtypes “>“>“>“>“>“>“>“>“>“>“>“>IgE, Ig“>“>“>“>“>“>1, IgG4“>“>“>“>“>“>“>“>“>“>“>“> are studied.“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>“>
T and B cell responses have been analy“>“>“>“>“>“>“>ed in various groups of sub“>“>“>“>ects ((Tiemessen MM, “>“>“>an Ieperen-Van “>ijk “>“>“>“>“>“>“>“>“>“>“>“>“>“>“>G, Bruijnzeel-“>“>“>“>“>“>“>“>“>oomen “>“>“>“>“>“>“>“>“>“>“>A, Garssen “>“>“>“>“>, Knol EF, Van “>“>offen E. Cows milk-specific T-cell reactivity of children with and without persistent cows milk allergy“>“>“>“>“>“>“>“>“>“>“>“>“> key role for IL-10. J Allergy Clin Immunol 2004;113(5):932-9)),((“>“>“>“>uiter B, Trgoat V, Mrabet L, Garssen J, Bruijnzeel-Koomen CA, Knol EF, Hoffen E. Characterization of T cell epitopes in alphas1-casein in cows milk allergic, atopic and non-atopic children. Clin E“>“>“>“>p Allergy 2006;36(3):303-10)),((Ruiter B, Knol EF, van “>eerven RJ, Garssen J, Bruijnzeel-Koomen CA, Knulst AC, van Hoffen E. Maintenance of tolerance to cows milk in atopic individuals is characterized by high levels of specific immunoglobulin G4. Clin Exp Allergy 2007;37(7):1103-10)):

Allergic individuals: have specific IgE towards the allergen of interest and clinical symptoms

    “>“>“>“>

  • “>ensitized non-allergic individuals: have specific IgE towards the allergen of interest but no clinical symptoms
  • Atopic individuals: IgE towards other allergens, but not to the allergen of interest
  • Non-atopic individuals: no family history of atopy, no elevated IgE

In vitro assays for functional IgE reactivity are available:

  • RBL assay: rat mast cell line transfected with the human IgE-receptor
  • Basophil degranulation assay: human basophil degranulation measured by histamine release or CD63 expression((Koppelman SJ, “>ensing M, Ertmann M, Knulst AC, Knol EF. Relevance of Ara h1, Ara h2 and Ara h3 in peanut-allergic patients, as determined by immunoglobulin E Western blotting, basophil-histamine release and intracutaneous testing: Ara h2 is the most important peanut allergen. Clin Exp Allergy 2004;34(4):583-90))

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