2016

Allergenicity and safety of recombinant human C1 esterase inhibitor in patients with allergy to rabbit or cow’s milk van den Elzen MT, van Os-Medendorp H, Röckmann-Helmbach H, van Hoffen E, Lebens AFM, van Doorn H, Klemans RJB, Bruijnzeel-Koomen CAFM, Hack CE, Kaufman L, et al. J Allergy Clin Immunol. 2016 Aug;138(2):476–81.e1

Allergenicity assessment strategy for novel food proteins and protein sources Verhoeckx K, Broekman H, Knulst A, Houben G. Regul Toxicol Pharmacol. 2016 Aug;79:118–24

Can we identify patients at risk of life-threatening allergic reactions to food? Turner PJ, Baumert JL, Beyer K, Boyle RJ, Chan C-H, Clark AT, Crevel RWR, DunnGalvin A, Fernández-Rivas M, Gowland MH, et al. Allergy. 2016 Sep;71(9):1241–55

Cofactors in allergic reactions to food: physical exercise and alcohol are the most important Versluis A, van Os-Medendorp H, Kruizinga AG, Blom WM, Houben GF, Knulst AC. Immunity, Inflamm Dis. 2016 Dec;4(4):392–400

Current challenges facing the assessment of the allergenic capacity of food allergens in animal models Bøgh KL, van Bilsen J, Głogowski R, López-Expósito I, Bouchaud G, Blanchard C, Bodinier M, Smit J, Pieters R, Bastiaan-Net S, et al. Clin Transl Allergy. 2016 Dec 16;6(1):21

Development of immune organs and functioning in humans and test animals: Implications for immune intervention studies Kuper CF, van Bilsen J, Cnossen H, Houben G, Garthoff J, Wolterbeek A. Reprod Toxicol. 2016 Sep;64:180–90

Evaluation of the sensitizing potential of food proteins using two mouse models Smit J, Zeeuw-Brouwer M de, van Roest M, de Jong G, van Bilsen J. Toxicol Lett. 2016;

Guided introduction after negative double-blind placebo-controlled peanut challenges in children van Erp FC, Knulst AC, Gorissen DMW, Kok IL, van der Ent CK, Meijer Y. J Allergy Clin Immunol Pract. 2016 Nov;

IgG1 Fc N-glycan galactosylation as a biomarker for immune activation de Jong SE, Selman MHJ, Adegnika AA, Amoah AS, van Riet E, Kruize YCM, Raynes JG, Rodriguez A, Boakye D, von Mutius E, et al. Sci Rep. 2016 Jun 16;6:28207

Intra- and inter-laboratory validation of an innovative huFcεRIα-RBL-2H3 degranulation assay for in vitro allergenicity assessment of whey hydrolysates Knipping K, van Roest M, Kruijssen L, Smits M, Teunis M, Cox L, de Jong N, Simons PJ, Boon L, Teshima R, et al. Toxicol Vitr. 2016 Jun;33:29–34

Kiwifruit cysteine protease actinidin compromises the intestinal barrier by disrupting tight junctions Grozdanovic MM, Čavić M, Nešić A, Andjelković U, Akbari P, Smit JJ, Gavrović-Jankulović M. Biochim Biophys Acta – Gen Subj. 2016;1860(3):516–26

Majority of shrimp-allergic patients are allergic to mealworm Broekman H, Verhoeckx KC, den Hartog Jager CF, Kruizinga AG, Pronk-Kleinjan M, Remington BC, Bruijnzeel-Koomen CA, Houben GF, Knulst AC. J Allergy Clin Immunol. 2016 Apr;137(4):1261–3

Modifying the infant’s diet to prevent food allergy Grimshaw K, Logan K, O’Donovan S, Kiely M, Patient K, van Bilsen J, Beyer K, Campbell DE, Garcia-Larsen V, Grabenhenrich L, et al. Arch Dis Child. 2017 Feb;102(2):179–86

Oral exposure to immunostimulating drugs results in early changes in innate immune parameters in the spleen. Kwast L, Fiechter D, Kruijssen L, Bleumink R, Ludwig I, Bol-Schoenmakers M, Smit J, Pieters R. J Immunotoxicol. 2016;1–13

Peanut protein structure, polyphenol content and immune response to peanut proteins in vivo are modulated by laccase Mihajlovic L, Radosavljevic J, Nordlund E, Krstic M, Bohn T, Smit J, Buchert J, Cirkovic Velickovic T. Food Funct. 2016;2357–66

Prioritisation of allergenic foods with respect to public health relevance Houben G, Burney P, Chan C-H, Crevel R, Dubois A, Faludi R, Klein Entink R, Knulst A, Taylor S, Ronsmans S. Food Chem Toxicol. 2016 Mar;89:8–18

Pros and Cons of Clinical Basophil Testing (BAT) Hoffmann HJ, Knol EF, Ferrer M, Mayorga L, Sabato V, Santos AF, Eberlein B, Nopp A, MacGlashan D. Curr Allergy Asthma Rep. 2016 Aug 13;16(8):56

Specific IgE to Jug r 1 has no additional value compared with extract-based testing in diagnosing walnut allergy in adults Blankestijn MA, Blom WM, Otten HG, Baumert JL, Taylor SL, Bruijnzeel-Koomen CAFM, Houben GF, Knulst AC, Klemans RJB. J Allergy Clin Immunol. 2016 Sep;

The IgE and basophil responses to Ara h 2 and Ara h 6 are good predictors of peanut allergy in children van Erp FC, Knol EF, Pontoppidan B, Meijer Y, van der Ent CK, Knulst AC. J Allergy Clin Immunol. 2017 Jan;139(1):358–60.e8

The mycotoxin deoxynivalenol facilitates allergic sensitization to whey in mice Bol-Schoenmakers M, Braber S, Akbari P, de Graaff P, van Roest M, Kruijssen L, Smit JJ, van Esch BCAM, Jeurink P V, Garssen J, et al. Mucosal Immunol. 2016;(February):1–10

The use of animal models to discover immunological mechanisms underpinning sensitization to food allergens Smit JJ, Noti M, O’Mahony L. Drug Discov Today Dis Model. 2016 Oct;