2005

Reversible denaturation of Brazil nut 2S albumin (Ber e1) and implication of structural destabilization on digestion by pepsin. Koppelman SJ, Nieuwenhuizen WF, Gaspari M, Knippels LM, Penninks AH, Knol EF, Hefle SL, de Jongh HH. J Agric Food Chem 2005;53(1):123-31.

Recent advances using rodent models for predicting human allergenicity. Knippels LM, Penninks AH. Toxicol Appl Pharmacol 2005;207(2 Suppl):157-60.

The effect of the food matrix on in vivo immune responses to purified peanut allergens. Van Wijk F, Nierkens S, Hassing I, Feijen M, Koppelman SJ, de Jong GA, Pieters R, Knippels LM. Toxicol Sci 2005;86(2):333-41.

CTLA-4 signaling regulates the intensity of hypersensitivity responses to food antigens, but is not decisive in the induction of sensitization. Van Wijk F, Hoeks S, Nierkens S, Koppelman SJ, van Kooten P, Boon L, Knippels LM, Pieters R. J Immunol 2005;174(1):174-9.

A mutant of the major apple allergen, Mal d 1, demonstrating hypo-allergenicity in the target organ by double-blind placebo-controlled food challenge. Bolhaar ST, Zuidmeer L, Ma Y, Ferreira F, Bruijnzeel-Koomen CA, Hoffmann-Sommergruber K, van Ree R, Knulst AC. Clin Exp Allergy 2005;35(12):1638-44.

In vivo assessment with prick-to-prick testing and double-blind, placebo-controlled food challenge of allergenicity of apple cultivars. Bolhaar ST, van de Weg WE, van Ree R, Gonzalez-Mancebo E, Zuidmeer L, Bruijnzeel-Koomen CA, Fernandez-Rivas M, Jansen J, Hoffmann-Sommergruber K, Knulst AC, Gilissen LJ. J Allergy Clin Immunol 2005;116(5):1080-6.

Thresholds of allergenic proteins in foods. Hourihane JO, Knulst AC. Toxicol Appl Pharmacol 2005;207(2 Suppl):152-6.

Purification and immunoglobulin E-binding properties of peanut allergen Ara h 6: evidence for cross-reactivity with Ara h 2. Koppelman SJ, de Jong GA, Laaper-Ertmann M, Peeters KA, Knulst AC, Hefle SL, Knol EF. Clin Exp Allergy 2005;35(4):490-7.

Severe allergy to sharon fruit caused by birch pollen. Bolhaar ST, van Ree R, Ma Y, Bruijnzeel-Koomen CA, Vieths S, Hoffmann-Sommergruber K, Knulst AC, Zuidmeer L.. Int Arch Allergy Immunol 2005;136(1):45-52.